Lyme Disease Research (non member) Database
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Introduction to Lyme Disease

LDRD Articles:

Chronic Lyme Disease
Lyme Disease Symptoms
Tick Bites and Lyme
Lyme Disease Treatment
Cure for Lyme Disease
Lyme Disease Rash


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LDRD Research Articles and Abstracts

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Research Articles:
Guidelines from the Infectious Diseases Society of America

Practice Guidelines for the Treatment of Lyme Disease.


Clinical Overview of Lyme Disease
Lyme Disease Eugene D. Shapiro1 and Michael A. Gerber2  1Departments of Pediatrics and of Epidemiology and Public Health and the Children’s Clinical Research Center, Yale University School of Medicine, New Haven, and 2Department of Pediatrics, University of Connecticut School of Medicine, Farmington, Connecticut.


Lyme Disease: The Great Imitator: Chiroweb.com

Lyme-Disease-The-Great-Imitator-Brad-McKechnie-DC-DACAN


Lyme Disease: Basic Facts: USA-CHPPM


Lyme-Disease-Fact-Sheet
Wisconsin Department of Health and Family Services.


Lyme disease cases on the rise
By Hema Easley The Journal News (Original publication: June 11, 2004)


Lyme-Disease-Research-Efforts-Division-of-Intramural-Research-National-Institute-of-Allergy-and-Infectious-Diseases
 The National Institute of Allergy and Infectious Diseases (NIAID) has had a longstanding commitment to conduct research on Lyme borreliosis, or Lyme disease, beginning more than 20 years ago when the cause of the disease was not yet known. In 1981, NIAID-funded research efforts resulted in identifying Borrelia burgdorferi bacteria as the causative agent of Lyme disease. Since then, basic and clinical research efforts have been expanded in scope to address many different aspects of this infectious disease.


National Library of Medicine and the National Institute of Health


Lyme Disease Pandemic

‘Lyme disease’: ancient engine of an unrecognized borreliosis pandemic? W. T. Harvey, P. Salvato Diversified Medical Practices, Houston, Texas, USA


Rebbecca Wells battling Lyme disease translates her illness Ya-Ya Sisterhood Sequel
 BETH FOUHY Associated Press Posted on March 30, 2005


Diagnoses of Lyme Disease
Diagnosis of Lyme Disease Division of Microbiology and Infectious Diseases
NIAID, in collaboration with the CDC and the Office of Rare Diseases, sponsored a conference on the laboratory diagnosis of Lyme disease in August 1998.


FDA-Public-Health-Advisory: Lyme Disease
Assays for Antibodies to Borrelia burgdorferi; Limitations, Use, and Interpretation for Supporting a Clinical Diagnosis of Lyme Disease.

New Laboratory Guidelines for Serologic Diagnosis of Lyme Disease
 Evaluation of the Two-Test Protocol. Thomas B. Ledue, Marilyn F. Collins, and Wendy Y. Craig.


Improved Serodiagnostic Testing for Lyme Disease

 Results of a Multicenter Serologic Evaluation.


Lyme-Disease-Test-Kits-Potential-for-Misdiagnosis
FDA Medical Bulletin * Summer 1999 * Final Issue


Testing

IGeneXLab.Inc
(html webpage)

Learn about the new testing facility, (Bowen Research Lab) in the Expert Interview Series.


Misdiagnoses of Lyme Disease

 
Appropriateness of Lyme Disease Serologic Testing Ramsey Annals of Family Medicine
Abstract Full Text (PDF) In Brief TRACK Comments: Submit a response TRACK Comments: View responses Alert me when
 this article is cited Appropriateness of Lyme Disease Serologic Testing Alan H. Ramsey, MD MPH&TM1,2, Edward A. Belongia, MD3, Po-Huang Chyou, PhD3 and Jeffrey P. Davis, MD1.


The Lyme disease controversy: Social and financial costs of misdiagnosis and mismanagement
Social and financial costs of misdiagnosis and mismanagement. •Download to Citation Manager L. H. Sigal Department of Medicine, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, New Brunswick, USA.


Improved Serodiagnostic Testing for Lyme Disease Results of Multicenter Serologic Evaluation
Emerging Infectious Diseases * Volume 2 * Number 2 April-June 1996.


Lyme Disease Misdiagnoses
By Marjorie Tietjen Director For Lyme Disease Concerns Common Cause Medical Research Foundation 10-13-3.


Quality of Lyme disease serology
Quality of Lyme disease serology Lessons from the German Proficiency Testing Program 1999–2001 A preliminary report* Klaus-Peter Hunfeld1, Gerold Stanek2, Eberhard Straube3, Hans-Jochen Hagedorn3, Christoph Schörner3, Fritz Mühlschlegel3, and Volker Brade1.


Symptoms of Lyme Disease


BarbourFish1
American Association for the Advancement of Science.


DVBID Symptoms or CDC Lyme Disease
CDC: Division of vector born diseases.


FSLyme
Massachusetts Department of Public Health. Public health fact sheet.


Lyme Disease Symptoms Diagnosis and Treatment
Penn State college of agricultural sciences.


Lyme Disease
Michigan Dept. of Natural Resources.


lymefact21
U.S. Department of Labor Occupational Safety and Health Administration.


MedlinePlus Medical Encyclopedia Lyme Disease
National Library of Medicine. Medical Encyclopedia.

Lyme Protocols
(Treatment)


burrascano_2005
JOSEPH J. BURRASCANO JR., M.D. President, East End Medical Associates, P.C. East Hampton, NY Board Member, International Lyme and Associated Diseases Society.


Guidelines for Treatment of Lyme:IDSA
Guidelines From the Infectious Diseases Society of America.


Practice Guidelines for the Treatment of Lyme Disease
Practice guidelines for the treatment of Lyme disease.


SAMENTO PROCOTOL FOR LYME BORRELIOSOS: Wm.-Lee-Cowden-MD
PROTOCOL FOR LYME BORRELIOSIS From Wm. Lee Cowden, MD.


Positive Health News Report: No 19
General diet and nutrition protocols for many health conditions.



Antibiotics & Lyme


Antibiotics and Early Lyme
 A Randomized, Double-Blind, Placebo-Controlled Trial Gary P. Wormser, MD; Roshan Ramanathan, MD, MPH; John Nowakowski, MD; Donna McKenna, RN, ANP; Diane Holmgren, RN; Paul Visintainer, PhD; Rhea Dornbush, PhD; Brij Singh, MD; and Robert B. Nadelman, MD.


Autoimmune Neurological Disease Role of Chronic Infections in Morbidity and Progression
 Prof. Garth L. Nicolson The Institute for Molecular Medicine (Website www.immed.org) 15162 Triton Lane, Huntington Beach, CA 92649-1401.


Clarithromiacin-in-Treatment-of-Early-Lyme
AYMOND J. DATTWYLER,1* EDGAR GRUNWALDT,2 AND BENJAMIN J. LUFT1 Lyme Disease Center, State University of New York at Stony Brook, Stony Brook, New York 11794-8161,1 and 440 South Ferry Road, Shelter Island, New York 11964.

Clinical Alert Chronic Lyme Disease Symptoms Not Helped by Intensive Antibiotic Treatment
National Institute of Allergy and Infectious Disease (NIAID) 12 June 2001.


Comparison of Cefroxime Axetil and Doxycycline Erythma Migrans
 STEVEN W. LUGER,1 PHILIP PAPARONE,2 GARY P. WORMSER,3 ROBERT B. NADELMAN,3 EDGAR GRUNWALDT,4 GEMA GOMEZ,5 MICHAEL WISNIEWSKI,5 AND JEFFREY J. COLLINS5*



Safety of Long Term Therapy with Penicillin and Penicillin Derivatives

U.S. Food and Drug Administration • Center for Drug Evaluation and Research.



Borrelia Burgdorferi

Bbsymptoms
 “The variable clinical manifestations have led to an awareness of this disorder as a ‘great imitator’ that must be considered in the differential diagnosis of numerous complaints, especially in those geographic areas where the spirochete is endemic.” Cooke WD; Dattwyler RJ. Complications of Lyme borreliosis. Annual Review of Medicine, 43:93-103. 1992.


Borrelia Burgdorferi Overview2


Borrelia-Spirochetes-Upregulate-Release
Borrelia Spirochetes Upregulate Release and Activation of Matrix Metalloproteinase Gelatinase B (MMP-9) and Collagenase 1 (MMP-1) in Human Cells


Borrelia-basics
BORRELIA History and overview

BB_Organism_Details
Borrelia Burgdorferi: Organism Details


Bb_Alzheimer
Borrelia burgdorferi persists in the brain in chronic lyme neuroborreliosis and may be associated with Alzheimer disease.


Antigenic_variation_in_Lyme_disease_borreliae_by_promiscuous_recombination_of_VMP-like_sequence_cassettes
Borrelia Burgdorferi: Antigenic variation in Lyme disease borreliae by promiscuous recombination of VMP-like sequence cassettes.

Lyme Co-infections


Rickettsia,_Chlamydia,_Mycoplasma

RICKETTSIA, CHLAMYDIA, MYCOPLASMA Overview



 CO-INFECTIONS IN LYME - Babesiosis, Ehrlichiosis, Bartonella. Other tick borne diseases - Tularemia, Tick Paralysis, relapsing fever and Rocky Mountain Spotted Fever


Bartonella_infections
Bartonella infections are an obscure group of diseases to most practitioners of Western medicine.


Dual Infection with Ehrlichia chaffeensis and a Spotted Fever Group Rickettsia: A Case Report



Ehrlichioses-CDC-gov

The Human Ehrlichioses in the United States Jennifer H. McQuiston, Christopher D. Paddock, Robert C. Holman, and James E. Childs Centers for Disease Control and Prevention, Atlanta, Georgia, USA.


IGeneX,_Inc._-_Ehrlichiosis

There are two forms of the disease caused by the Ehrlichia species: E. chaffeensis and E. phagocytophilia, which cause the human diseases, Human Monocytic Ehrlichiosis (HME) and Human Granulocytic Ehrlichiosis (HGE), respectively.


IGeneX,_Inc._-_Babesiosis
Detection of Babesia IgM and IgG Antibodies in Serum by the Indirect Immunofluorescent Antibody Assay (IFA)


Babesiosis-Coinfection
 When to Suspect and How to Monitor Babesiosis ELEFTHERIOS MYLONAKIS, M.D.,Massachusetts General Hospital, Boston,Massachusetts


Spirochetes_and_Rickettsia

Dr. Jorge Benach Chlamydia and Rickettsia


Ehrlichia-_September-2003
Ehrlichia: Cancer Ehrlichia By Gil Ash • September 2003 Newsletter
Integrative Treatments for Lyme Disease

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Colloidal Silver Super Antibiotic Rediscovery
Natural Health and Longevity Resource Center.


Hyperbaric-Oxygen-Therapy_HBOT
Dr. Elmer M. Cranton, MD.


AUTOIMMUNE NEUROLOGICAL DISEASES ROLE OF CHRONIC INFECTIONS IN MORBIDITY AND PROGRESSION
 DIAGNOSIS AND THERAPY OF CHRONIC SYSTEMIC COINFECTIONS IN LYME DISEASE AND OTHER TICK-BORNE INFECTIOUS DISEASES  Prof. Garth L. Nicolson.


Bee_Venom_Protocol_For_Lyme_Disease
Bee Venom Protocol For Lyme Disease.


Effects of Hyperbaric Oxygen Therapy On Lyme Disease
Effects of Hyperbaric Oxygen Therapy On Lyme Disease by William P. Fife, Ph. D. 29 January 1998.


Gale Encyclopedia of Alternative Medicine Lyme disease

Gale Encyclopedia of Alternative Medicine.


FROM-PENICILLIN-TO-MILD-SILVER-PROTEIN
 FROM "PENICILLIN TO "MILD SILVER PROTEIN" AN ANSWER TO LYME DISEASE "WITHOUT ANTIBIOTICS" By: Dr. William Burgdorfer, Ph.D. Rocky Mountain Laboratories, Division of N.l.H.


Lyme Disease and Bovine Colostrum


Chronic Infections Some Products and Treatments that Work
Chronic Infections: Some Products and Treatments that Work Lyme disease and chronic illnesses are completely reversible, thanks to... The Incredible Healing Action of One Simple Herb Dr. Robert Jay Rowen's SECOND OPINION Vol. XIII, No. 12, December 2003.



Nutrition, Diet & Lyme Disease

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a growing collection of resources for nutirtion and diet.
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Integrated-Approach-DAN
HEALING LYME DISEASE: An Integrated Approach to Curing Chronic Infection. Daniel A. Kinderlehrer, M.D.


Lyme-Disease-Nutrition-EDU
University of Maryland Medical Center.


Symptom-of-Nutritional-Deficiency
Dr. Charles L. Crist, MD. All Rights Reserved.


Treating_Lyme_Disease_Naturally
Dr. Cindee Gardner Ph.D.


Nutrition-Diet-Lyme
Dietary Considerations for Patients with Chronic Illnesses and Multiple Chronic Infections by Prof. Garth L. Nicolson, Dr. Richard Ngwenya ChronicFatigue.com.


Positive-Health-News-Report-No-19

General diet and nutrition protocols for many health conditions.


Promoting mitochondrial health

Promoting Mitochondrial Health Nutrients That Optimize Cellular Energy
By Dale Kiefer



Lifestyle and Lyme Disease

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Living with Lyme
By Bill Sontag The News-Herald December 29, 2003


Additional Resources
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New-Vaccine-Targets-Lyme-Disease-New-Hope-for-Diminishing-Great-Masquerader
 by Carol Lewis